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Publications

Please find links to all reprints below or visit Google Scholar

26

26

2023

General and Comparative Endocrinology

Functional characterization of melanocortin 2 receptor (Mc2r) from a lobe- finned fish (Protopterus annectens) and insights into the molecular evolution of melanocortin receptors

Shaughnessy CA, Le K, Myhre VD, Dores RM

25

25

2023

General and Comparative Endocrinology

Molecular and pharmacological analysis of the melanocortin-2 receptor and its accessory proteins Mrap1 and Mrap2 in a Squalomorph shark, the Pacific spiny dogfish

Bouyoucos IA, Shaughnessy CA, Anderson WG, Dores, RM

24

24

2023

General and Comparative Endocrinology

Hypothalamus-pituitary-interrenal (HPI) axis signaling in Atlantic sturgeon (Acipenser oxyrinchus) and sterlet (Acipenser ruthenus)

Shaughnessy CA, Myhre V, Hall DJ, McCormick SD, Dores RM

23

23

2023

General and Comparative Endocrinology

Trends in the evolution of the elasmobranch melanocortin-2 receptor: insights from structure/function studies on the activation of whale shark Mc2r

Hoglin BE, Miner MV, Erdenebayar U, Shaughnessy CA, Dores RM

22

22

2023

Canadian Journal of Fisheries and Aquatic Sciences

Juvenile sea lamprey (Petromyzon marinus) have a wide window of elevated salinity tolerance that is eventually limited during springtime warming

Shaughnessy CA, McCormick SD

21

21

2022

Biomolecules

Structure/function studies on the activation motif of two non-mammalian Mrap1 orthologs, and observations on the phylogeny of Mrap1, including a novel characterization of an Mrap1 from the chondrostean fish, Polyodon spathula

Dores RM, McKinley G, Meyers A, Martin M, Shaughnessy CA

20

20

2022

Biomolecules

Human melanocortin-2 receptor: identifying a role for residues in the TM4, EC2, and TM5 domains in activation and trafficking as a result of co-expression with the accessory protein, Mrap1 in Chinese hamster ovary cells

Davis PV, Shaughnessy CA, Dores RM

19

19

2022

General and Comparative Endocrinology

A basal actinopterygian melanocortin receptor: molecular and functional characterization of an Mc2r ortholog from the Senegal bichir (Polypterus senegalus)

Shaughnessy CA, Jensen MF, Dores RM

18

18

2022

JCI Insight

IL-13-programmed airway tuft cells produce PGE2, which promotes CFTR-dependent mucociliary function

Kotas ME, Moore C, Gurrola II JG, Pletcher S, Goldberg AN, Alvarez R, Yamato S, Bratcher PE, Shaughnessy CA, Zeitlin PL, Zhang I, Li Y, Montgomery MT, Lee K, Cope E, Locksley RM, Seibold MA, Gordon ED

17

17

2022

Fish Physiology and Biochemistry

The isosmotic point as critical salinity limit for growth and osmoregulation, but not survival, in the wolf eel Anarrhichthys ocellatus

Shaughnessy CA, Balfry SK, Bystriansky JS

16

16

2022

Journal of Cystic Fibrosis

Net benefit of ivacaftor during prolonged tezacaftor/elexacaftor exposure in vitro

Shaughnessy CA, Zeitlin PL, Bratcher PE

15

15

2022

American Journal of Physiology – Lung Cellular and Molecular Physiology

Receptor-mediated activation of CFTR via prostaglandin signaling pathways in the airway

Shaughnessy CA, Yadav S, Bratcher PE, Zeitlin PL

14

14

2021

Scientific Reports

Tissue and salinity specific Na+/Cl-cotransporter (NCC) orthologues involved in the adaptive osmoregulation of sea lamprey (Petromyzon marinus)

Barany A, Shaughnessy CA, Pelis RM, Fuentes J, Mancera JM, McCormick SD

13

13

2021

Scientific Reports

Elexacaftor is a CFTR potentiator and acts synergistically with ivacaftor during acute and chronic treatment

Shaughnessy CA, Zeitlin PL, Bratcher PE

12

12

2021

Journal of Experimental Biology

11-Deoxycortisol is a stress responsive and gluconeogenic hormone in a jawless vertebrate, the sea lamprey (Petromyzon marinus)

Shaughnessy CA, McCormick SD

11

11

2021

General and Comparative Endocrinology

Corticosteroid control of Na+/K+-ATPase in the intestine of the sea lamprey (Petromyzon marinus)

*Barany A, *Shaughnessy CA, McCormick SD

10

10

2021

BMJ Open Respiratory Research

Down-regulation of the epithelial sodium channel (ENaC) in human airway epithelia in response to low temperature incubation

*Yadav S, *Shaughnessy CA, Zeitlin PL, Bratcher PE

9

9

2021

Journal of Experimental Zoology A – Ecological and Integrative Physiology

Molecular mechanisms of Cl-transport in fishes: new insights and their evolutionary context

Shaughnessy CA, Breves JP

8

8

2020

Physiological Reports

Effect of apical chloride concentration on the measurement of responses to CFTR modulation in airway epithelia cultured from nasal brushings

Bratcher PE, Yadav S, Shaughnessy CA, Thornell IM, Zeitlin PL

7

7

2020

Scientific Reports

11-Deoxycortisol controls hydromineral balance in the most basal osmoregulating vertebrate, sea lamprey (Petromyzon marinus)

Shaughnessy CA, Barany A, McCormick SD

6

6

2020

American Journal of Physiology – Regulatory, Integrative, and Comparative Physiology

Osmoregulatory role of the intestine in the sea lamprey (Petromyzon marinus)

Barany A, Shaughnessy CA, Fuentes J, Mancera JM, McCormick SD

5

5

2020

American Journal of Physiology – Regulatory, Integrative, and Comparative Physiology

Functional characterization and osmoregulatory role of gill Na+/K+/2Cl- cotransporter (NKCC1) in sea lamprey (Petromyzon marinus), a basal vertebrate

Shaughnessy CA, McCormick SD

4

4

2020

Estuaries and Coasts

Upper thermal tolerance and heat shock protein response of juvenile American shad (Alosa sapidissima)

*Bayse S, *Shaughnessy CA, Regish A, McCormick SD

3

3

2018

Journal of Experimental Biology

Reduced thermal tolerance during salinity acclimation in brook trout (Salvelinus fontinalis) can be rescued by prior treatment with cortisol

Shaughnessy CA, McCormick SD

2

2

2017

Canadian Journal of Zoology

Survival and osmoregulation of the purple marsh crab (Sesarma reticulatum) at varying salinity and pH

Shaughnessy CA, Anderson EC, Kasparian M, LaMontagne JM, Bystriansky JS

1

1

2015

Journal of Experimental Biology

Interaction of osmoregulatory and acid-base compensation in white sturgeon (Acipenser transmontanus) during exposure to aquatic hypercarbia and elevated salinity

Shaughnessy CA, Baker DW, Brauner CJ, Morgan JD, Bystriansky JS

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